Construction of urease-negative mutants of Yersinia enterocolitica serotypes O:3 and o:8: role of urease in virulence and arthritogenicity.
نویسندگان
چکیده
Yersinia enterocolitica serotype O:3 and O:8 urease-negative mutants unable to express the 19-kDa beta subunit of urease were constructed and tested for virulence and arthritogenicity. Our results indicate that urease is needed for full virulence in oral infections and that it is not an arthritogenic factor in the rat model.
منابع مشابه
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ورودعنوان ژورنال:
- Infection and immunity
دوره 68 2 شماره
صفحات -
تاریخ انتشار 2000